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  • 產(chǎn)品名稱：anti-HIV-1Tatantibody(Biotin)

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  • 產(chǎn)品廠商：DIATHEVA
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簡單介紹：
anti-HIV-1Tatantibody(Biotin)
詳情介紹：
Immunogen Purified recombinant protein HIV-I tat expressed in E. coli
Specificity The antibody detects HIV1 tat protein and GST tat fusion protein. HIVI tat protein in sera or plasma and in cell culture supernatant
Characteristics Tat is a regulatory protein of HIV-1 virus, well conserved among different isolates. Tat is produced early after infection and it's essential for virus replication and infectivity. Tat protein is also immunogenic and antibodies (Ab) against tat have been found to correlate with delayed disease progression and may exert protective effects by inhibiting both HIV-1 replication and the effects of extracellular tat. Moreover, tat is efficiently taken up by monocyte-derived dendritic cells, promotes their maturation and antigen presenting since it enters the major histocompatibility complex class I pathway. Finally, murine vaccination with a biologically active tat protein has been shown to be safe, immunogenic and elicits anti-tat neutralizing Ab and CTL.
Purification Purified by protein A affinity chromatography and conjugated by NHS-biotin.
Alternative Name HIV1 Tat
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Buffer Supplied in PBS and 0.05?% v/v glycerol
Storage 4 °C