Purpose
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PF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.
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Characteristics
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Target: FAK inhibitor Receptor: FAK,PYK2,CDK2/CDK3/CDK1/CDK7
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Purification
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All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
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Purity
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100?%
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Formula
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C21H20F3N7O3S
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Solubility
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Soluble in DMSO
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