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  • 產(chǎn)品名稱:P7C3

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簡單介紹:
P7C3
詳情介紹:
Purpose The P7C3 class of neuroprotective aminopropyl carbazoles has been shown to block neuronal cell death in models of neurodegeneration. We now show that P7C3 molecules additionally preserve axonal integrity after injury, before neuronal cell death occurs, in a rodent model of blast-mediated traumatic brain injury (TBI). This protective quality may be linked to the ability of P7C3 molecules to activate nicotinamide phosphoribosyltransferase, the rate-limiting enzyme in nicotinamide adenine dinucleotide salvage.
Characteristics Receptor: nicotinamide phosphoribosyltransferase
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 98?%
Formula C21H18Br2N2O
Solubility Soluble in DMSO
Molecular Weight 474.19 g/mol
CAS-No 301353-96-8
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months