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  • 產(chǎn)品名稱：SGI-1776freebase

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SGI-1776freebase
詳情介紹：
Purpose SGI-1776 free base is a novel ATP competitive inhibitor of Pim1 with IC50 of 7 nM in a cell-free assay, 50- and 10-fold selective versus Pim2 and Pim3, also potent to Flt3 and haspin. Phase 1.
Characteristics Target: Pim inhibitor, FLT3 inhibitor
Receptor: Pim1, FLT3, Pim3,Pim2
Status: Experimental
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 100?%
Formula C20H22F3N5O
Solubility DMSO 81 mg/mL,Ethanol 81 mg/mL,Water <1 mg="" ml="" <="" td="">
Molecular Weight 405.42 g/mol
CAS-No 1025065-69-3
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months