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  • 產(chǎn)品名稱：Drospirenone

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簡單介紹：
Drospirenone
詳情介紹：
Purpose Drospirenone is a synthetic progestin that is an analog to spironolactone. It is found in a number of birth control formulations. Drospirenone differs from other synthetic progestins in that its pharmacological profile in preclinical studies shows it to be closer to the natural progesterone. As such it has anti-mineralocorticoid properties, counteracts the estrogen-stimulated activity of the renin-angiotensin-aldosterone system, and is not androgenic. It was shown in animal studies that drospirenone exhibits antiandrogenic activity judging from accessory sex gland growth in castrated, androgen-treated, juvenile rats.
Characteristics Source of Compound: synthetic, ZK-30595
Target: Progesterone receptor agonist, Androgen receptor antagonist,COX inhibitor, Mineralocorticoid receptor antagonist
Receptor: Progesterone receptor, Androgen receptor, Prostaglandin G/H synthase 2, Mineralocorticoid receptor
Status: USP, INN, BAN
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 98?%
Formula C24H30O3
Solubility DMSO 73 mg/mL,Ethanol 11 mg/mL,Water <1 mg="" ml="" <="" td="">
Molecular Weight 366.49 g/mol
CAS-No 67392-87-4
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months