Purpose
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PD173074 is a potent FGFR1 inhibitor with IC50 of ~25 nM and also inhibits VEGFR2 with IC50 of 100-200 nM in cell-free assays, ~1000-fold selective for FGFR1 than PDGFR and c-Src.
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Characteristics
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Target: FGFR inhibitor, VEGFR inhibitor, Src inhibitor Receptor: FGFR1,VEGFR2,c-Src,EGFR
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Purification
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All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
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Purity
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99.30?%
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Formula
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C28H41N7O3
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Solubility
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200 mM in DMSO and ethanol
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