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  • 產(chǎn)品名稱：Nilotinib(AMN-107)

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Nilotinib(AMN-107)
詳情介紹：
Purpose Nilotinib, also known as AMN107, is a tyrosine kinase inhibitor under investigation as a possible treatment for chronic myelogenous leukemia (CML). In June 2006, a Phase I clinical trial found nilotinib has a relatively favorable safety profile and shows activity in cases of CML resistant to treatment with imatinib (Gleevec?), another tyrosine kinase inhibitor currently used as a first-line treatment.
Characteristics Tradename: AMN-107
Source of Compound: synthetic
Target: Bcr-Abl inhibitor,Mast/stem cell GFR Kit agonist
Receptor: Bcr-Abl ,Mast/stem cell GFR Kit
Status: FDA
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 99.00?%
Formula C28H22F3N7O
Solubility DMSO 27 mg/Ml,Water <1 mg="" ml="" <="" td="">
Molecular Weight 529.52 g/mol
CAS-No 641571-10-0
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months