產(chǎn)品詳情

  • 產(chǎn)品名稱：ASP-3026

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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ASP-3026
詳情介紹：
Purpose A potent, and ATP-competitive inhibitor of ALK (Anaplastic Lymphoma Receptor Tyrosine Kinase)
Characteristics ASP-3026 is a potent, and ATP-competitive inhibitor of ALK (Anaplastic Lymphoma Receptor Tyrosine Kinase) with IC?? value of 3.5 nM. It also inhibits ROS (IC?? = 8.9 nM) and ACK (IC?? = 5.8 nM). ASP3026 has been shown to overcome Crizotinib (Cat. No. 1934) resistance in non-small cell lung cancer.
Purity ≥ 98?% by HPLC
Chemical Name 2-N-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-4-N-(2-propan-2-ylsulfonylphenyl)-1,3,5-triazine-2,4-diamine
Formula C??H??N?O?S
Permeability Cell-permeable
Solubility DMSO
Molecular Weight 580.74 g/mol
CAS-No 1097917-15-1
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months