產(chǎn)品詳情

  • 產(chǎn)品名稱：GSK343

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
GSK343
詳情介紹：
Characteristics A potent histone H3-lysine 27 (H3K27) methyltransferase EZH2 inhibitor (IC50= 4 nM). Diplays 1000-fold selectivity for other HMTs except EZH1 (60-fold selectivity). GSK343 inhibits H3K27 methylation in HCC1806 cells with an IC50of < 200nM (measured by immunofluorescence).
Purity ≥ 99?% by HPLC
Chemical Name 1-Isopropyl-N-((6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl)-6-(2-(4-methylpiperazin-1-yl)pyridine-4-yl)-1H-indazole-4-carboxamide
Formula C??H??N?O?
Permeability Cell-permeable
Molecular Weight 541.69 g/mol
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and moisture
Storage -20 °C
Expiry Date 36 months
Supplier Images
image for GSK343 (ABIN1685581) GSK343