Characteristics
|
PubChem CID: 9903 Molecular Formula: C??H??O? Cell Premeable: No Molecular Formula: C24H40O3. Lithocholic acid (LCA) is a hydrophobic secondary bile acid that is primarily formed in the intestine by the bacterial 7-alpha dehydroxylation of chenodeoxycholic acid. Acts as a detergent to solubilize fats for absorption. Known to display both carcinogenic and apoptotic activities. Also binds to the p53 s of both MDM2 and MDM4 with a five-fold preference for MDM4. Synonyms: 3alpha-Hydroxy-5beta-cholan-24-oic acid, 3alpha-Hydroxy-5beta-cholanic acid, 5beta-Cholan-24-oic acid-3alpha-ol, LCA
|