產(chǎn)品詳情

  • 產(chǎn)品名稱：TAK-733

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡單介紹：
TAK-733
詳情介紹：
Purpose Selective, non-ATP competitive, allosteric MEK inhibitor
Characteristics Crystalline solid
Molecular formular: C17H15F2IN4O4
Purity ≥ 98?% by HPLC
Chemical Name (R)-3-(2,3-dihydroxypropyl)-6-fluoro-5-(2-fluoro-4-iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione
Formula C??H??F?IN?O?
Permeability Cell-permeable
Molecular Weight 504.23 g/mol
CAS-No 1035555-63-5
Comment

Synonyms:
(R)-3-(2,3-dihydroxypropyl)-6-fluoro-5-(2-fluoro-4-iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione
A potent, selective, non-ATP competitive, allosteric MEK inhibitor. TAK-733 selectively binds to and inhibits the activity of MEK1/2, preventing the activation of MEK1/2-dependent effector proteins and transcription factors, which may result in the inhibition of growth factor-mediated cell signaling and tumor cell proliferation
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
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