產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：WZ4002

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠(chǎng)商：Biovision
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
WZ4002
詳情介紹：
Purpose A third generation EGFR inhibitor.
Characteristics Pale yellow solid
Molecular formular: C25H27ClN6O3
Purity ≥ 98?% by HPLC
Chemical Name N-(3-(5-chloro-2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)pyrimidin-4-yloxy)phenyl)acrylamide
Formula C??H??ClN?O?
Permeability Cell-permeable
Molecular Weight 494.97 g/mol
CAS-No 1213269-23-8
Comment

Synonyms:
N-(3-(5-chloro-2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)pyrimidin-4-yloxy)phenyl)acrylamide
A third generation EGFR inhibitor. Selectively inhibits mutant EGFR T790M. Inhibits EGFR phosphorylation and induces siginificant tumor regressionin murine model of EGFR T790M. WZ4002 can overcome anoikis resistance in EGFR-mutant lung adenocarcinomas more effectively than Src inhibitors
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
Supplier Images
image for WZ4002 (ABIN1889018) WZ4002