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Synonyms: (2E)-N-(4,5-dihydro-2-thiazolyl)-3-(4-ethylphenyl)-2-propenamide, CID-50910523 ML-243 is a selective inhibitor of cancer stem cells. Displays 32-fold selective inhibition of a breast cancer stem cell-like cell line (EC = 2.0 μM) over a control (mammary epithelial) cell line (EC = 64 μM). It weakly antagonizes the adenosine A2A receptor (IC = 10 μM) and has no effect on 68 other targets commonly used in drug discovery for lead profiling
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