產(chǎn)品詳情

  • 產(chǎn)品名稱：L-685,458

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡單介紹：
L-685,458
詳情介紹：
Characteristics Cell-permeable. A potent and selective gamma-secretase inhibitor (IC50 = 17 nM).Displays > 50-fold selectivity over a range of aspartyl, serine and cysteine proteases. Exhibits equal potency for inhibition of Abeta40 and Abeta42 peptides (IC50 values are 48 and 67 nM respectively in human neuroblastoma cells).
Purity ≥ 98?% by HPLC
Chemical Name 5S)-(tert-Butoxycarbonylamino)-6-phenyl-(4R)-hydroxy-( 2R)-benzylhexanoyl)-L-leucyl-L-phenylalaninamide
Formula C??H??N?O?
Permeability Cell-permeable
Molecular Weight 672.85 g/mol
CAS-No 292632-98-5
Restrictions For Research Use only
Format Liquid
Concentration 0.672 μg/μL
Buffer DMSO
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
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