產(chǎn)品詳情

  • 產(chǎn)品名稱：EZSolution?Nec-1s

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
EZSolution?Nec-1s
詳情介紹：
Purpose A potent necroptosis inhibitor.
Brand EZSolution?
Characteristics Molecular formular: C13H12ClN3O2
Purity ≥ 96?% by LC-MS
Chemical Name 5-((7-Cl-1H-indol-3-yl)methyl)-3-methylimidazolidine-2,4-dione); 7-Cl-O-Nec-1
Formula C??H??ClN?O?
Permeability Cell-permeable
Molecular Weight 277.71 g/mol
Comment

Synonyms:
5-((7-Cl-1H-indol-3-yl)methyl)-3-methylimidazolidine-2,4-dione), 7-Cl-O-Nec-1
A potent necroptosis inhibitor. Displays higher activity in inhibiting necroptosis in Jurkat cells than Nec-1 (Cat. No. 1864) (EC = 210 nM versus EC = 490 nM), as well as showing no nonspecific cytotoxicity at high concentrations (approx. 100 mM). More useful for in-cell and in vivo experiments compared to Nec-1
Restrictions For Research Use only
Format Liquid
Concentration 10 mM
Buffer anhydrous DMSO
Handling Advice Protect from light and moisture
Storage -20 °C
Expiry Date 12 months
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image for EZSolution? Nec-1s (ABIN1888962) EZSolution? Nec-1s