產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：EZSolution?GDC-0449

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠(chǎng)商：Biovision
  • 產(chǎn)品文檔：
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EZSolution?GDC-0449
詳情介紹：
Purpose A potent inhibitor of Smoothened (SMO)
Brand EZSolution?
Characteristics Molecular formular: C19H14Cl2N2O3S
Purity ≥ 98?% by HPLC
Chemical Name 2-Chloro-N-(4-chloro-3-(pyridine-2-yl)phenyl)-4-(methylsulfonyl)benzamide; HhAntag691
Formula C??H??Cl?N?O?S
Permeability Cell-permeable
Molecular Weight 421.3 g/mol
CAS-No 879085-55-9
Comment

Synonyms:
2-Chloro-N-(4-chloro-3-(pyridine-2-yl)phenyl)-4-(methylsulfonyl)benzamide, HhAntag691
A potent inhibitor of Smoothened (SMO), a key mediator of Hedgehog (Hh) signaling pathway. Inhibition of SMO renders the transcription factor GLI inactive, thus preventing the expression of genes that mediate the role of Hh on tumor growth
Restrictions For Research Use only
Format Liquid
Concentration 10 mM
Buffer anhydrous DMSO
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 12 months
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image for EZSolution? GDC-0449 (ABIN1888967) EZSolution? GDC-0449