產(chǎn)品詳情

  • 產(chǎn)品名稱：EZSolution?GW2580

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡單介紹：
EZSolution?GW2580
詳情介紹：
Purpose A small-molecule, ATP-competitive inhibitor of cFMS kinase
Brand EZSolution?
Characteristics Molecular formular: C20H22N4O3
Purity ≥ 99?% by HPLC
Chemical Name 5-(3-Methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine
Formula C??H??N?O?
Permeability Cell-permeable
Molecular Weight 366.41 g/mol
CAS-No 870483-87-7
Comment

Synonyms:
5-(3-Methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine
A small-molecule, ATP-competitive inhibitor of cFMS kinase, at 60 nM it inhibits human cFMS kinase completely in vitro and was inactive against 26 other kinases. GW2580 also inhibits lipopolysaccharide (LPS)-induced TNF production in mice, but not LPS-induced TNF production in freshly isolated human monocytes and mouse macrophages in vitro
Restrictions For Research Use only
Format Liquid
Concentration 10 mM
Buffer anhydrous DMSO
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 12 months
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