產(chǎn)品詳情

  • 產(chǎn)品名稱：SAHA

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡單介紹：
SAHA
詳情介紹：
Characteristics Potent, reversible inhibitor of histone deacetylase 1 (HDAC1) and 3 (HDAC3). Induces cell growth arrest at both G1 and G2 phases. Induces apoptosis.
Purity ≥ 99?%
Chemical Name Vorinostat, Suberanilohydroxamic Acid, MK-0683
Formula C14H20N2O3
Permeability Cell-permeable
Molecular Weight 264.3 g/mol
CAS-No 149647-78-9
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 24 months
Supplier Images
image for SAHA (ABIN628982) SAHA
Product cited in: Buglio, Khaskhely, Voo, Martinez-Valdez, Liu, Younes: "HDAC11 plays an essential role in regulating OX40 ligand expression in Hodgkin lymphoma." in: Blood, Vol. 117, Issue 10, pp. 2910-7, 2011 (PubMed).

Eades, Yao, Yang, Zhang, Chumsri, Zhou: "miR-200a regulates SIRT1 expression and epithelial to mesenchymal transition (EMT)-like transformation in mammary epithelial cells." in: The Journal of biological chemistry, Vol. 286, Issue 29, pp. 25992-6002, 2011 (PubMed).

Eades, Yang, Yao, Zhang, Zhou: "miR-200a regulates Nrf2 activation by targeting Keap1 mRNA in breast cancer cells." in: The Journal of biological chemistry, Vol. 286, Issue 47, pp. 40725-33, 2011 (PubMed).