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  • 產品名稱：Triptolide

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Triptolide
詳情介紹：
Characteristics Triptolide, a diterpenoid triepoxyde, a purified component of a traditional Chinese medicine, inhibits transcriptional activation of NF- kappaB and downregulates the expression of various NF- kappaB-regulated genes. Displays Immunosuppressive, anti-inflammatory, anti-angiogenic and antitumor activity. A combination of TRAIL and triptolide enhance apoptosis in cholangiocarcinoma cell lines.
Purity ≥ 97?% by HPLC
Chemical Name TPL
Formula C??H??O?
Permeability Cell-permeable
Molecular Weight 360.4 g/mol
CAS-No 38748-32-2
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 24 months
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image for Triptolide (ABIN629037) Triptolide
Product cited in: Villica?a, Cruz, Zurita: "The genetic depletion or the triptolide inhibition of TFIIH in p53-deficient cells induces a JNK-dependent cell death in Drosophila." in: Journal of cell science, Vol. 126, Issue Pt 11, pp. 2502-15, 2013 (PubMed).