產(chǎn)品詳情
簡單介紹:
Okadaicacid
詳情介紹:
Characteristics | A Potent inhibitor of protein phosphatases 1 and 2A in numerous cell types. Does not affect activity of acid phosphatase, alkaline phosphatase and tyrosine phosphatase. Non-phorbol type tumor promoter. Induces apoptosis in human breast carcinoma cells (MB-231 and MCF-7) and in myeloid cells, but inhibits glucocorticoid-induced apoptosis in T-cell hybridomas. |
Purity | > 98?% |
Chemical Name | OA |
Formula | C??H??O?? |
Permeability | Cell-permeable |
Molecular Weight | 805 g/mol |
CAS-No | 78111-17-8 |
Restrictions | For Research Use only |
Format | Solid |
Handling Advice | Protect from moisture. Tumor promoter |
Storage | -20 °C |
Expiry Date | 12 months |
Supplier Images |
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Product cited in: |
Huang, Lin, Chang, Lu, Hsu, Wong, Wang: "Human JC virus small tumour antigen inhibits nucleotide excision repair and sensitises cells to DNA-damaging agents." in: Mutagenesis, Vol. 30, Issue 4, pp. 475-85, 2015 (PubMed).
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