產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：Dasatinib(BMS-354825,Sprycel)

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠(chǎng)商：Biovision
  • 產(chǎn)品文檔：
你添加了1件商品 查看購(gòu)物車(chē)
簡(jiǎn)單介紹：
Dasatinib(BMS-354825,Sprycel)
詳情介紹：
Characteristics Dasatinib is a multi-kinase inhibitor with potent activity against BCR-ABL kinase (IC50 < 1 nM) and Src family kinases (IC50 = 0.2-1.1 nM). Dasatinib also inhibits Lyn (IC50 = 8.5 nM) and Src (IC50 = 3.0 nM) kinase activities in vitro using 0.1 mg/mL poly (Glu4-Tyr) as the substrate.
Purity ≥ 99?% by HPLC
Chemical Name BMS-354825, Sprycel
Formula C??H??ClN?O?S
Permeability Cell-permeable
Molecular Weight 488.01 g/mol
CAS-No 302962-49-8
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and moisture
Storage -20 °C
Expiry Date 24 months
Supplier Images
image for Dasatinib (BMS-354825, Sprycel) (ABIN412169) Dasatinib (BMS-354825, Sprycel)
Product cited in: Kanou, Oneyama, Kawahara, Okimura, Ohta, Ikeda, Shintani, Okumura, Okada: "The transmembrane adaptor Cbp/PAG1 controls the malignant potential of human non-small cell lung cancers that have c-src upregulation." in: Molecular cancer research : MCR, Vol. 9, Issue 1, pp. 103-14, 2011 (PubMed).