產(chǎn)品詳情

  • 產(chǎn)品名稱：Bosutinib(SKI-606)

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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Bosutinib(SKI-606)
詳情介紹：
Characteristics Bosutinib (SKI-606) is a novel tyrosine kinase inhibitor. Bosutinib can overcome not only Bcr-Abl-dependent mechanisms of resistance, but also those that are Bcr-Abl-independent.It is used to treat patients with chronic myelogenous leukemia (CML) who demonstrate resistance to Imatinib or develop resistance during treatment.
Purity ≥ 99?% by HPLC
Chemical Name SKI-606
Formula C??H??Cl?N?O?
Permeability Cell-permeable
Molecular Weight 530.45 g/mol
CAS-No 380843-75-4
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and moisture
Storage -20 °C
Expiry Date 24 months
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image for Bosutinib (SKI-606) (ABIN412165) Bosutinib (SKI-606)
Product cited in: Lee, Jeng, Chen, Chung, Yuan: "Gas6/Axl pathway promotes tumor invasion through the transcriptional activation of Slug in hepatocellular carcinoma." in: Carcinogenesis, Vol. 35, Issue 4, pp. 769-75, 2014 (PubMed).