產(chǎn)品詳情

  • 產(chǎn)品名稱：TrichostatinA

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡單介紹：
TrichostatinA
詳情介紹：
Specificity Isolated from Streptomyces hygroscopicus
Characteristics Potent, reversible inhibitor of histone deacetylase. Mediates the activation of O6- methylguanine-DNA methyltransferase (MGMT). May be involved in cell cycle progression of several cell types, induces cell growth arrest at both G1 and G2/M phases. In some cases induces apoptosis.
Purity ≥ 99?%
Chemical Name TSA, [R-(E,E)]-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
Formula C??H??N?O?
Permeability Cell-permeable
Molecular Weight 302.4 g/mol
CAS-No 58880-19-6
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 24 months
Supplier Images
image for Trichostatin A (ABIN412199) Trichostatin A
Product cited in: Chen, Bellew, Yao, Stefkova, Dipp, Saifudeen, Bachvarov, El-Dahr: "Histone deacetylase (HDAC) activity is critical for embryonic kidney gene expression, growth, and differentiation." in: The Journal of biological chemistry, Vol. 286, Issue 37, pp. 32775-89, 2011 (PubMed).