產(chǎn)品詳情

  • 產(chǎn)品名稱：IKK-εKinaseInhibitorII

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
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簡單介紹：
IKK-εKinaseInhibitorII
詳情介紹：
Purpose An IKK-ε kinase inhibitor
Characteristics A benzimidazole analog that acts as a potent and selective inhibitor of IKK-epsilon kinase (IC50 = 40 nM), displays >125-fold selectivity over IKK-alpha and IKK-beta.
Purity ≥ 97?% by HPLC
Chemical Name 5-?(5,?6-?dimethoxy-?1H-?benzimidazol-?1-?yl)-?3-?[[2-?(methylsulfonyl)phenyl]methoxy]-?2-?thiophenecarbonitrile
Formula C??H??N?O?S?
Permeability Cell-permeable
Solubility DMSO
Molecular Weight 469.53 g/mol
CAS-No 862812-98-4
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
Supplier Images
image for IKK-ε Kinase Inhibitor II (ABIN629117) IKK-ε Kinase Inhibitor II
Product cited in: Palchetti, Starace, De Cesaris, Filippini, Ziparo, Riccioli: "Transfected poly(I:C) activates different dsRNA receptors, leading to apoptosis or immunoadjuvant response in androgen-independent prostate cancer cells." in: The Journal of biological chemistry, Vol. 290, Issue 9, pp. 5470-83, 2015 (PubMed).