Background
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Immunoglobulin M is the largest antibody isotype and the first to be secrected against an initial exposure to antigen. IgM is predominantly produced in the spleen. IgM is formed from covalently linking 5 immunoglobulins together. Due to this large size, IgM is typically isolated to the serum. Human IgM (myeloma) Fc5μ fragment consists of only the μ (mu) chain of the Fc fragment.
Synonyms: Human immunoglobulin M fragment, Fc(F,μ), (Fc),5μ
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