產(chǎn)品詳情

  • 產(chǎn)品名稱：Cortisol

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  • 產(chǎn)品廠商：BioLeaf
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Cortisol
詳情介紹：
Characteristics Purified Recombinant Cortisol
11beta, 17alpha, 21-Trihydroxypregn-4-ene-3,20-dione
Purity > 98 % pure
Target Type Hormone
Background Cortisol (hydrocortisone) is a steroid hormone, or glucocorticoid, produced by the adrenal gland. It is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis, suppress the immune system, and aid in fat, protein and carbohydrate metabolism. It also decreases bone formation. During pregnancy, increased production of cortisol between weeks 30-32 initiates production of fetal lung surfactanct to promote maturation of the lungs. Various synthetic forms of cortisol are used to treat a variety of different diseases.
Description: 11beta, 17alpha, 21-Trihydroxypregn-4-ene-3,20-dione.
Alternative Names: 11beta, 21-triol-3, 20-dione protein, 17alpha, Reichstein's substance M, 17-Hydroxycorticosterone protein, Kendall's compound F, Cortisol, 20-dione protein, 4-Pregnene-11beta protein, 21-Trihydroxypregn-4-ene-3 protein, 17alpha
Molecular Weight 362.46 kDa
Research Area Signaling, Hormones
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute at 1 mg/mL in ethanol.
Buffer Supplied as a lyophilized powder.
Handling Advice Avoid repeated freeze/thaw cycles.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Product cited in: Leung, Chan, Bosgoed, Lehmann, Renneberg, Lehmann, Renneberg: "One-step quantitative cortisol dipstick with proportional reading." in: Journal of immunological methods, Vol. 281, Issue 1-2, pp. 109-18, 2003 (PubMed).