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  • 產品名稱：TLRDetectionSet

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  • 產品廠商：ProSci-Inc
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TLRDetectionSet
詳情介紹：
Purification Antibodies are supplied as affinity chromatography purified IgG.
Components TLR1 Antibody (NT), (50 μg)
TLR2 Antibody (NT), (50 μg)
TLR3 Antibody (CT), (50 μg)
TLR4 Antibody (NT), (50 μg)
TLR5 Antibody (CT), (50 μg)
TLR6 Antibody (IN), (50 μg)
TLR7 Antibody (IN), (50 μg)
TLR8 Antibody (IN), (50 μg)
TLR9 Antibody (IN), (50 μg)
TLR10 Antibody (IN), (50 μg)
Background Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules to activate various kinases and transcription factors so the organism can respond to potential infection. These adaptor molecules include MyD88, TIRAP, TIRP, TOLLIP, and TRIF. These molecules interact with and activate the IL-1R-associated kinase (IRAK) family, which then activates TNF receptor associated factor (TRAF)-6, and ultimately leads to the activation of NF-?oB. While most TLRs utilize more than one adaptor, certain adaptor molecules are essential for individual TLR signaling, e.g., TLR4 signaling is dependent on TIRP expression.
Application Notes These polyclonal antibodies can be used for detection of TLR adaptor proteins by Western blot at 1 μg/mL to 4 μg/Ml, Immunohistochemistry/Immunocytochemistry, and Immunoflourescence
Optimal dilutions for each application to be determined by the researcher.
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer PBS containing 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Stable at 4 °C for three months, store at -20 °C for up to one year.
Expiry Date 12 months