產(chǎn)品詳情
  • 產(chǎn)品名稱:Piceatannol

  • 產(chǎn)品型號:
  • 產(chǎn)品廠商:ArborAssays
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簡單介紹:
Piceatannol
詳情介紹:
Characteristics Activator of SIRT1
Inhibits NF-kB activation
Induces apoptosis
Background Activator of human deacetylase SIRT1. Anti-inflammatory, immunomodulatory and antiproliferative agent that inhibits p56lck and syk protein tyrosine kinases and inhibits TNF-induced NF-kB activation and gene expression. Piceatannol is a resveratrol analog formed by the cytochrome P450-catalyzed hydroxylation of resveratrol. Piceatannol exhibits potent anticancer properties by inducing apoptosis in BJAB Burkitt-like lymphoma cells with an ED50 value of 25 μM. Piceatannol also exhibits anti-proliferative and anti-inflammatory effects by inhibiting the activity of a wide range of tyrosine and serine/threonine protein kinases and suppressing NF-kB activation through inhibition of IkBa kinase.
CAS-No 10083-24-6
Restrictions For Research Use only
Storage 4 °C
Supplier Images
 image for Piceatannol (ABIN1439971) Piceatannol