產(chǎn)品詳情

  • 產(chǎn)品名稱：Apicidin

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：ArborAssays
  • 產(chǎn)品文檔：
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簡單介紹：
Apicidin
詳情介紹：
Characteristics Potent HDAC Inhibitor
Blocks Cell Cycle G1
HIV-1 Promoter
Background Potent inhibitor of histone deacetylase (HDAC) activity and proliferation. Induces cell cycle arrest at the G1 phase. At 100 nM it induces a long lasting hyperacetylation of histone H4 while that induced by trichostatin is transient. Stimulates apoptosis. Apoptosis is induced via induction of Fas/Fas ligand. Displays potent antiangiogenic effects and dramatically decreases HIF-1a protein levels and transcriptional activity in human and mouse tumor cell lines. Apicidin is a fungal toxin that has broad spectrum activity against Apicomplexan parasites.
CAS-No 183506-66-3
Restrictions For Research Use only
Storage -20 °C
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image for Apicidin (ABIN1439974) Apicidin