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  • 產(chǎn)品名稱：Mouseanti-Rat(Rattus)IgG1(HeavyChain),(Chaingamma)Antibody(HRP)

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  • 產(chǎn)品廠商：Acris-antibodies
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簡單介紹：
Mouseanti-Rat(Rattus)IgG1(HeavyChain),(Chaingamma)Antibody(HRP)
詳情介紹：
Clone MARG1-2
Isotype IgG1
Purification Affinity Chromatography
Background Immunoglobulin G (IgG), is one of the most abundant proteins in human serum with normal levels between 8-17?mg/mL in ***** blood. IgG is important for our defence against microorganisms and the molecules are produced by B lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions, to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 10e11 variants. Immunoglobulins, or antibodies, are a complex, heterogeneous mixture of proteins that exhibit two fundamental types of structural variation. Subtle structural differences in their antigen combining sites, or variable regions, account for their unique antigen binding specificities.Synonyms: Rat Immunoglobulin G1
Research Area Secondary Antibodies
Application Notes ELISA: 0.5?μg/mL.

Other applications not tested.
Otimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer PBS,?pH 7.4 containing 0.01?% Thiomersal as preservative and 50?% Glycerol as stabilizer.
Handling Advice Avoid repeated freezing and thawing. Dilute only prior to immediate use
Centrifuge product if not completely clear after standing at room temperature.
Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -28 °C for longer.
Background publications Pelegrí, Castell, Serra, Rabanal, Rodríguez-Palmero, Castellote, Franch: "Prevention of adjuvant arthritis by the W3/25 anti-CD4 monoclonal antibody is associated with a decrease of blood CD4(+)CD45RC(high) T cells." in: Clinical and experimental immunology, Vol. 125, Issue 3, pp. 470-7, 2001 (PubMed).