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  • 產(chǎn)品名稱:Mouseanti-HumanIg(LightChain),(Chainkappa)Antibody

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  • 產(chǎn)品廠商:Acris-antibodies
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Mouseanti-HumanIg(LightChain),(Chainkappa)Antibody
詳情介紹:
Immunogen Human IgG-kappa myeloma protein
Clone TB28-2
Isotype IgG1
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Protein-A affinity chromatography
Alternative Name Immunoglobulin
Background Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda, both having a molecular weight of 22.5?kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30.
Research Area Secondary Antibodies, Virology
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer PBS,?pH ~7.4, 15 mM Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Storer the antibody at 2-8 °C for up to one month or (in aliqouts) at -20 °C for longer.
Background publications Davis, Karl, Swan, Unlu, Goldberg: "Capabilities and limitations of pupil-plane filters for superresolution and image enhancement." in: Optics express, Vol. 12, Issue 17, pp. 4150-6, 2009 (PubMed).

Kiyotaki, Cooper, Bertoli, Kearney, Kubagawa: "Monoclonal anti-Id antibodies react with varying proportions of human B lineage cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 138, Issue 12, pp. 4150-8, 1987 (PubMed).

Product cited in: Jourdan, Caraux, De Vos, Fiol, Larroque, Cognot, Bret, Duperray, Hose, Klein: "An in vitro model of differentiation of memory B cells into plasmablasts and plasma cells including detailed phenotypic and molecular characterization." in: Blood, Vol. 114, Issue 25, pp. 5173-81, 2009 (PubMed).

B?ttcher, Ritgen, Buske, Gesk, Klapper, Hoster, Hiddemann, Unterhalt, Dreyling, Siebert, Kneba, Pott et al.: "Minimal residual disease detection in mantle cell lymphoma: methods and significance of four-color flow cytometry compared to consensus IGH-polymerase chain reaction at initial staging and for ..." in: Haematologica, Vol. 93, Issue 4, pp. 551-9, 2008 (PubMed).

Karandikar, Aquino, McKenna, Kroft: "Transient myeloproliferative disorder and acute myeloid leukemia in Down syndrome. An immunophenotypic analysis." in: American journal of clinical pathology, Vol. 116, Issue 2, pp. 204-10, 2001 (PubMed).

Nakamura, Kubagawa, Cooper: "Heterogeneity of immunoglobulin-associated molecules on human B cells identified by monoclonal antibodies." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 18, pp. 8522-6, 1992 (PubMed).