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  • 產(chǎn)品名稱：Mouseanti-HumanIgG(FdRegion)Antibody(Biotin)

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  • 產(chǎn)品廠商：Acris-antibodies
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Mouseanti-HumanIgG(FdRegion)Antibody(Biotin)
詳情介紹：
Immunogen Human IgG Fd
Clone HP6045
Isotype IgG1
Cross-Reactivity (Details) Species reactivity (tested):Human.
Background The Fd region of Human Immunoglobulins is located at the N-terminal part of the heavy chain and is an essential component of the antigen-binding fragment Fab. Fd, like the light chain, contains a C-terminal constant (CH1) and N- terminal variable (VH) domain. The hypervariable regions in both the light chain and Fd determine the specificity of the Fab.Synonyms: Human Immunoglobulin G
Research Area Immunology, Secondary Antibodies
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Restrictions For Research Use only
Concentration 0.1 mg/mL
Buffer PBS containing 0.02?% Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5?mg/mL.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -28 °C for longer.
Background publications Papadea, Check, Reimer: "Monoclonal antibody-based solid-phase immunoenzymometric assays for quantifying human immunoglobulin G and its subclasses in serum." in: Clinical chemistry, Vol. 31, Issue 12, pp. 1940-5, 1986 (PubMed).

Reimer, Phillips, Aloisio, Moore, Galland, Wells, Black, McDougal: "Evaluation of thirty-one mouse monoclonal antibodies to human IgG epitopes." in: Hybridoma, Vol. 3, Issue 3, pp. 263-75, 1985 (PubMed).

Jefferis, Reimer, Skvaril, de Lange, Ling, Lowe, Walker, Phillips, Aloisio, Wells: "Evaluation of monoclonal antibodies having specificity for human IgG sub-classes: results of an IUIS/WHO collaborative study." in: Immunology letters, Vol. 10, Issue 3-4, pp. 223-52, 1985 (PubMed).