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  • 產(chǎn)品名稱：anti-DPP4antibody(Dipeptidyl-Peptidase4)(PE)

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簡單介紹：
anti-DPP4antibody(Dipeptidyl-Peptidase4)(PE)
詳情介紹：
Clone H207-1082
Isotype IgG2a
Specificity This antibody recognises CD26, which is also known as thymocyte-activating molecule (THAM).
Cross-Reactivity (Details) Species reactivity (tested):Mouse.
Purification Affinity Chromatography on Protein G
Alternative Name CD26 / DPP4 (DPP4 Antibody Abstract)
Background Murine CD26 is a type II integral membrane dipeptidyl-peptidase that is expressed at the cell surface as a heterodimer, of approximately 220 kDa, and has a soluble form in the plasma. The CD26?Molecule is a multifunctional glycoprotein that has ectopeptidase activity and is also reported to be involved in cell adhesion, signal transduction in T lymphocytes and HIV infection. CD26 is differentially expressed on developing thymocytes and is upregulated on activated T-cells but is not expressed on resting and thioglycollate stimulated macrophages. Expression of CD26 has also been reported on cells from a variety of non-haematopoietic tissues including liver, intestine and kidney.Synonyms: ADABP, ADCP2, Adenosine deaminase complexing protein 2, DPP IV, Dipeptidyl peptidase 4, Dipeptidyl peptidase IV, T-cell activation antigen CD26, TP103
Gene ID 13482
NCBI Accession NP_001153015
UniProt P28843
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity
Application Notes Flow Cytometry: The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Reconstitution Restore with 0.25?mL (Cat.-No SM2264RT) or 1?mL (Cat.-No SM2264R) distilled water
Concentration 0.1 mg/mL
Buffer PBS,?pH 7.4, 0.09?% Sodium Azide, 5?% Sucrose and 1?% BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice This product is photosensitive and should be protected from light
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Background publications Cinar, Senol, Ozen: "Immunohistochemical study on distribution of endocrine cells in gastrointestinal tract of flower fish (Pseudophoxinus antalyae)." in: World journal of gastroenterology : WJG, Vol. 12, Issue 42, pp. 6874-8, 2006 (PubMed).

Marguet, Baggio, Kobayashi, Bernard, Pierres, Nielsen, Ribel, Watanabe, Drucker, Wagtmann: "Enhanced insulin secretion and improved glucose tolerance in mice lacking CD26." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 12, pp. 6874-9, 2000 (PubMed).

Vivier, Marguet, Naquet, Bonicel, Black, Li, Bernard, Gorvel, Pierres: "Evidence that thymocyte-activating molecule is mouse CD26 (dipeptidyl peptidase IV)." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 147, Issue 2, pp. 447-54, 1991 (PubMed).