Purpose
|
Antineoplastic bifunctional, DNA alkylating agent that causes DNA damage by cross-linking DNA and proteins. Causes double-base lesions mainly at 5'-GA-3' and, to a lesser extent, at 5'-GG-3' sequences. Forms an intrastrand cross-link at the 5'-GA-3' sequence, and to monoalkylation. Induces normal human fibroblast senescence selectively through Erk and p38 pathways
|
Characteristics
|
Tradename: MYLERAN Source of Compound: synthetic Target: DNA Alkylating Receptor: DNA Status: USP, INN, BAN, JAN
|
Purification
|
All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
|
Purity
|
98?%
|
Formula
|
C6H14O6S2
|
Solubility
|
Soluble in DMSO
|