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  • 產品名稱：AG-014699phosphate

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  • 產品廠商：Biovision
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AG-014699phosphate
詳情介紹：
Purpose A potent PARP1 inhibitor
Characteristics AG-014699 phosphate is a potent, cell-permeable inhibitor of PARP1 with Ki of 1.4 nM. It selectively binds to PARP 1 and inhibits the PARP1-mediated DNA repair, thus potentiating the genomic instability and apoptosis. Displays antineoplastic activity.
Purity ≥ 98?% by HPLC
Chemical Name 8-Fluoro-2-(4-((methylamino)methyl)phenyl)-4,5-dihydro-1H-azepino[5,4,3-cd]indol-6(3H)-one phosphate; Rucaparib; PF-01367338
Formula C??H??FN?O?P
Permeability Cell-permeable
Solubility DMSO (~20 mg/ml)
Molecular Weight 421.36 g/mol
CAS-No 459868-92-9
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 36 months