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  • 產品名稱：3-DeazaneplanocinA

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  • 產品廠商：Biovision
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3-DeazaneplanocinA
詳情介紹：
Characteristics A lysine methyltransferase EZH2 (KMT63) inhibitor. DZNep is a selective inhibitor of trimethylation of lysine 27 on histone H3 (H3K27 me3) and lysine 20 on histone H4 (H4K27 me3). DZNep treatment of cultured human AML cells induces increased expression of the cell-cycle regulators p21, p27, and FBXO32, leading to cell cycle arrest and apoptosis.
Synonyms: DZNep, NSC 617989, 5R-(4-amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1S,2R-diol
Purity ≥ 98?%
Chemical Name DZNep; NSC 617989; 5R-?(4-?amino-?1H-?imidazo[4,?5-?c]pyridin-?1-?yl)-?3-?(hydroxymethyl)-?3-?cyclopentene-?1S,?2R-?diol
Formula C??H??N?O?
Permeability Cell-permeable
Molecular Weight 262.26 g/mol
CAS-No 102052-95-9
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
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