產(chǎn)品詳情
  • 產(chǎn)品名稱:RO4929097

  • 產(chǎn)品型號:
  • 產(chǎn)品廠商:Biovision
  • 產(chǎn)品文檔:
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RO4929097
詳情介紹:
Characteristics RO4929097 is a small molecule gamma-secretase inhibitor (IC50 = 4 nM). It binds to gamma-secretase and blocks the activation of Notch receptors, which may inhibit tumor cell proliferation. RO4929097 inhibits Notch processing in tumor cells as measured by the reduction of intracellular Notch expression by Western blot. RO4929097 produces a less transformed and flattened slower-growing phenotype but does not induce apoptosis or block tumor cell proliferation.
Purity ≥ 98?% by HPLC
Formula C??H??F?N?O?
Permeability Cell-permeable
Molecular Weight 469.4 g/mol
CAS-No 847925-91-1
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
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 image for RO4929097 (ABIN956503) RO4929097