Comment
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Synonyms: 4-Dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide A potent Akt and PDPK1 (3-Phosphoinositide Dependent Protein Kinase 1) inhibitor. PH 427 binds to the pleckstrin homology (PH) domain of Akt and PDPK1 signaling with significant in vivo antitumor activity and minimal toxicity
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