產(chǎn)品詳情

  • 產(chǎn)品名稱：Cyclopaminetartrate

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡單介紹：
Cyclopaminetartrate
詳情介紹：
Purpose Inhibitor of Hedgehog (Hh) signaling pathway
Characteristics Crystalline solid
Molecular formular: C58H88N2O10
Purity ≥ 98?%
Chemical Name (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-1,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-Octadecahydro-3',6',10,11b-tetramethylspiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-3-ol tartrate; 11-Deoxojervine Tartrate; (3β,23β)-17,23-Epoxy- veratraman-3-ol Tartrate; 11-Deoxyjervine Tartrate; CycT
Formula C??H??N?O??
Permeability Not-permeable
Molecular Weight 973.32 g/mol
CAS-No 1178510-81-0
Comment

Synonyms:
Cyclopamine tartrate
Cyclopamine tartrate is a water-soluble derivative of the Hedgehog (Hh) signaling pathway inhibitor Cyclopamine (Cyc) (Cat. No.1578). Displays higher inhibitory activity for Hh signaling-dependent motor neuron differentiation than did Cyc (IC = 50 nM/L for CycT vs. 300 nM/L for Cyc). CycT-treated mice shows tumor shrinkage and decreased expression of Hh target genes
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 24 months
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