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  • 產(chǎn)品名稱：Goatanti-HumanIgA(SecretoryComponent),(Free&Bound)Antibody(Biotin)

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  • 產(chǎn)品廠商：Acris-antibodies
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簡單介紹：
Goatanti-HumanIgA(SecretoryComponent),(Free&Bound)Antibody(Biotin)
詳情介紹：
Immunogen Purified free Human Secretory component isolated from pooled milk is used for immunization. Freund's complete adjuvant is used in the first step of the immunization procedure.
Isotype IgG
Characteristics Molar Ratio: Biotin/IgG aprox. 4.5
Purification Hyperimmune antisera with strong precipitating activity are selected for Fractionation by Salt-Precipitation and purification of the IgG fraction by DEAE-Chromatography.
Background Secretory component is present in human secretions bound to secretory IgA (sIgA) and in free form. Secretory IgA (sIgA) functions as a dimer or polymer and accounts for almost all specific mucosal antibody activity. A molecule of sIgA is made up of two molecules of IgA, one J chain and one SC (MW 65,000). The dimer IgA is transported into secretions by its binding to the SC on the epithelial cells. Under normal conditions, sIgA contains both subclasses IgA1 and IgA2, since both are capable of binding SC. SC also has an affinity for polymeric IgM.Synonyms: Human Immunoglobulin A
Research Area Immunology, Secondary Antibodies
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Restrictions For Research Use only
Format Liquid
Reconstitution Restore by adding 1.0?mL of sterile distilled water.
Concentration 10.0 mg/mL
Buffer PBS,?pH 7.2 without preservatives and foreign proteins
Preservative Without preservative
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one week or (in aliquots) at -28 °C for longer.